E ai ki tētahi rōpū rangahau tahi mai i te Kura Hauora o Harvard (HMS) me te Hōhipera Whānui o MIT kua tutuki i a rātou te whakatikatika i te putanga o te taiaho moroiti mā te whakamahi i te tikanga whakairo PEC, ā, he "whakamiharo" tēnei puna hou mō te nanophotonics me te koiora.
(Ka taea te whakarite i te putanga o te taiaho moroiti mā te tikanga whakairo PEC)
I ngā mara onanophotonicsme te rongoā koiora, te kōpae itingā taiahoā, kua tino whai hua ngā taiaho nanodiskngā pūtake māramame ngā tirotiro. I roto i ētahi tono pēnei i te whakawhitiwhiti whakaahua i runga i te maramara, te whakaahua koiora i runga i te maramara, te kite matū koiora, me te tukatuka mōhiohio whakaahua irahiko, me whakatutuki e rātou te putanga laser hei whakatau i te roanga ngaru me te tika o te roopu tino-whaiti. Heoi, he uaua tonu te hanga i ngā laser kōpae moroiti me te nano o tēnei roanga ngaru tika i runga i te tauine nui. Ko ngā tukanga hanga nano o nāianei e whakauru ana i te matapōkere o te diameter kōpae, e uaua ai te whiwhi i tētahi roanga ngaru kua whakaritea i roto i te tukatuka me te whakaputa papatipu laser. Ināianei, he rōpū kairangahau mai i te Kura Hauora o Harvard me te Pokapū Wellman o te Hōhipera Whānui o Massachusetts mōRongoā Optoelectronickua whakawhanake i tētahi tikanga whakairo optochemical (PEC) auaha e āwhina ana ki te whakarite tika i te roanga ngaru taiaho o tētahi taiaho moroiti me te tika o te iti-nanometer. Kua whakaputaina te mahi i roto i te puka Advanced Photonics.
Te whakairo whakaahua-matū
E ai ki ngā pūrongo, mā te tikanga hou a te tīma ka taea te hanga i ngā reera kōpae-iti me ngā rarangi reera nanodisk me ngā roangaru tukunga tika, kua whakaritea kētia. Ko te mea nui ki tēnei putanga hou ko te whakamahinga o te whakairo PEC, e whakarato ana i tētahi huarahi whai hua me te tauine hei whakatikatika i te roangaru o te reera kōpae-iti. I roto i ngā hua o runga ake nei, i angitu te tīma ki te whiwhi i ngā kōpae-iti indium Gallium arsenide phosphating kua hipokina ki te silica i runga i te hanganga pou indium phosphide. Kātahi ka whakatikatikahia e rātou te roangaru reera o ēnei kōpae-iti kia tika ki tētahi uara kua whakaritea mā te mahi whakairo photochemical i roto i tētahi otinga kua whakaranua o te waikawa whanariki.
I tirotirohia hoki e rātou ngā tikanga me ngā hihiri o ngā whakairo whakaahua matū motuhake (PEC). Hei whakamutunga, i whakawhitihia e rātou te rarangi kōpae iti kua whakaritea ki te roangaru ki runga i te papa polydimethylsiloxane hei whakaputa i ngā matūriki taiaho motuhake, motuhake me ngā roangaru taiaho rerekē. Ko te kōpae iti ka puta he whānuitanga whānui rawa o te tukunga taiaho, me terēserii runga i te pou iti iho i te 0.6 nm me te matūriki wehea iti iho i te 1.5 nm.
Te whakatuwhera i te tatau ki ngā tono hauora
Mā tēnei hua ka huaki te tatau ki ngā tono nanophotonics hou me te koiora. Hei tauira, ka taea e ngā taiaho kōpae moroiti takitahi te mahi hei paewaehere ā-tinana-whatu mō ngā tauira koiora kanorau, ka taea ai te tapanga o ngā momo pūtau motuhake me te arotahi ki ngā ngota motuhake i roto i te tātaritanga maha. Kei te whakahaerehia te tapanga momo pūtau motuhake mā te whakamahi i ngā tohu koiora tikanga, pērā i ngā fluorophores waro, ngā ira ira, me ngā pītiti fluorescent, he whānui ngā raina tukunga. Nō reira, he torutoru noa ngā momo pūtau motuhake ka taea te tapanga i te wā kotahi. He rerekē, ka taea e te tukunga mārama porowhita tino whaiti o te taiaho kōpae moroiti te tautuhi i ngā momo pūtau maha atu i te wā kotahi.
I whakamātauhia e te tīma, ā, i whakaatu angitu i ngā matūriki taiaho microdisk kua tino whakatikatikahia hei tohu koiora, mā te whakamahi i ēnei hei tapanga i ngā pūtau epithelial ū noa kua whakatipuria hei MCF10A. Mā te tukunga ultra-wideband, ka taea e ēnei taiaho te huri i te biosensing, mā te whakamahi i ngā tikanga hauora me te whatu kua whakamātauhia pērā i te whakaahua cytodynamic, te cytometry rere, me te tātaritanga maha-omics. Ko te hangarau e hangai ana ki te whakairo PEC he tohu i tētahi whanaketanga nui i roto i ngā taiaho microdisk. Ko te kaha o te tikanga, me tōna tika o te subnanometer, e whakatuwhera ana i ngā āheinga hou mō ngā tono maha o ngā taiaho i roto i ngā nanophotonics me ngā taputapu hauora, tae atu ki ngā waehere pae mō ngā taupori pūtau motuhake me ngā ngota tātari.
Wā tuku: Hanuere-29-2024